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KMID : 1044520180810010042
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Tuberculosis and Respiratory Diseases
2018 Volume.81 No. 1 p.42 ~ p.48
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Development of Prediction Equation of Diffusing Capacity of Lung for Koreans
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Hwang Yong-Il
Park Yong-Bum
Yoon Hyoung-Kyu
Lim Seong-Yong
Kim Tae-Hyung
Park Joo-Hun
Lee Won-Yeon
Park Seong-Ju
Lee Sei-Won
Kim Woo-Jin
Kim Ki-Uk
Shin Kyeong-Cheol
Kim Do-Jin
Kim Hui-Jung
Kim Tae-Eun
Yoo Kwang-Ha
Shim Jae-Jeong
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Abstract
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Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans.
Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study.
Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=?10.4433?0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507?0.02374×age (year)?0.00233×heights (cm). For women the prediction equations were described as followed: DLco=?12.8895?0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516?0.02219×age (year)?0.01377×heights (cm). All equations were internally validated by k-fold cross validation method.
Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.
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KEYWORD
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Korean, Pulmonary Diffusing Capacity, Diffusion, Carbon Monoxide
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